CSAC Bulletin Article

Booster Shots Recommended for Immunocompromised Individuals

August 26, 2021

The U.S. Department of Health and Human Services (HHS) issued a recommendation for a single booster shot of COVID-19 vaccine six months after completing the initial two-dose regimen of the Comirnaty or Moderna vaccines. This recommendation applies only to those who are severely or moderately immunocompromised and who have received an mRNA vaccine.

This includes people who:

  • Get active cancer treatment for tumors or cancers of the blood
  • Got an organ transplant and are taking medicine to suppress the immune system
  • Got a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system
  • Have moderate or severe primary immunodeficiency (such as DiGeorge syndrome, Wiskott-Aldrich syndrome)
  • Have advanced or untreated HIV infection
  • Get active treatment with high-dose corticosteroids or other drugs that suppress immune response

The California Department of Public Health (CDPH) has issued a helpful Q&A for those who are immune-compromised and are considering an additional dose of a COVID-19 vaccine. About 700,000 Californians may qualify for a third dose. Patients are urged to consult with their medical provider on the efficacy of a booster shot, and appointments may be booked through the state’s MyTurn online appointment system.

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